CTL-12

CAT: 0931-T78873-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T78873-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Others, Fatty Acid Synthase

Related Pathways

Others, Metabolism

Bioactivity

CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase. It upregulates caspase-9 and the apoptosis marker Bax, while downregulating the anti-apoptotic marker Bcl-xL. By inhibiting de novo lipogenesis, CTL-12 thwarts tumor cells' metabolic requirements and is frequently employed in breast and colorectal cancer studies [1].

Molecular Formula

C22H21ClN4O4

Molecular Weight

440.88

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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