CTL-12

• Target:

  Others|||Fatty Acid Synthase

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 ?M), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase. It upregulates caspase-9 and the apoptosis marker Bax, while downregulating the anti-apoptotic marker Bcl-xL. By inhibiting de novo lipogenesis, CTL-12 thwarts tumor cells' metabolic requirements and is frequently employed in breast and colorectal cancer studies [1].

• Molecular Formula:

  C22H21ClN4O4

• Molecular Weight:

  440.88

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C