CTL-06

• Target :

  Others|||Fatty Acid Synthase

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 ?M, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase and modulates apoptotic and anti-apoptotic markers by upregulating caspase-9 and Bax and downregulating Bcl-xL. Additionally, CTL-12 suppresses de novo lipogenesis, curtailing the metabolic needs of tumor cells, with utilization in breast and colorectal cancer studies [1].

• Smiles :

  O=C(C1=CC(N=C(C2=C(O)C=CC(Cl)=C2)N3)=C3C=C1)N4CCN(C(OCC)=O)CC4

• Molecular Formula :

  C21H21ClN4O4

• Molecular Weight :

  428.87

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C