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CTL-06

CAT: 0931-T78872-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T78872-01Size:5 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||Fatty Acid Synthase
Related Pathways
Others|||Metabolism
Bioactivity
CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 ?M, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase and modulates apoptotic and anti-apoptotic markers by upregulating caspase-9 and Bax and downregulating Bcl-xL. Additionally, CTL-12 suppresses de novo lipogenesis, curtailing the metabolic needs of tumor cells, with utilization in breast and colorectal cancer studies [1].
Smiles
O=C(C1=CC(N=C(C2=C(O)C=CC(Cl)=C2)N3)=C3C=C1)N4CCN(C(OCC)=O)CC4
Molecular Formula
C21H21ClN4O4
Molecular Weight
428.87
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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