ORN 06

• Description:

  ORN 06 (Compound R-0006), a U-rich single-stranded RNA (containing 6 repeats of the UUG sequence motif), is a TLR7/8 agonist. ORN 06 stimulates human TLR7/8-mediated or murine TLR7-mediated immunity[1].

• UNSPSC:

  12352208

• Target:

  Toll-like Receptor (TLR)

• Type:

  Oligonucleotides

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/orn-06.html

• Solubility:

  10 mM in H2O

• Smiles:

  [ORN06]

• References & Citations:

  [1]Forsbach A, Nemorin JG, Montino C, et al. Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses. J Immunol. 2008;180 (6) :3729-3738.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  No Development Reported

• Isoform:

  TLR7

• CAS Number:

  [1116698-32-8]