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HPK1-IN-39

CAT: 0804-HY-149520Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149520Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HPK1-IN-39 (Compound 10n) is a selective HPK1 Inhibitor (IC50: 29 nM) . HPK1-IN-39 inhibits the phosphorylation of SLP76. HPK1-IN-39 can be used for research of cancer immunotherapy[1].
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-39.html
Solubility
10 mM in DMSO
Smiles
NC(CC1)CCC1N2N=C(C3=CC=NC=C3)C(C2=N4)=CN=C4NC5=CC(C(C)(C)OC6=O)=C6C=C5
Molecular Formula
C26H27N7O2
Molecular Weight
469.54
References & Citations
[1]Zhang J, et al. Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors. Bioorg Chem. 2023 Nov;140:106811.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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