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GPX4-IN-8

CAT: 0804-HY-149455-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149455-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GPX4-IN-8 (compound A80) is a potent GPX4 inhibitor. GPX4-IN-8 shows antiproliferative activity[1].
CAS Number
2703776-20-7
UNSPSC
12352005
Target
Glutathione Peroxidase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gpx4-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C1(CCOCC1)C(NCC2=CC=CC=C2)=O)C3=CC(Cl)=CC=C3)C#C
Molecular Formula
C22H21ClN2O3
Molecular Weight
396.87
References & Citations
[1]Sheldon Cao, et al. Gpx4 inhibitors, pharmaceutical compositions thereof, and their use for treating gpx4-mediated diseases. WO2021183702A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GPX4

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