NIR-FP

• UNSPSC Description:

  NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O2-. O2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nir-fp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(CC(/C=C/C1=CC=C(OS(=O)(C(F)(F)F)=O)C=C1)=C/2)(C)CC2=C(C#N)\C#N

• Molecular Weight:

  422.42

• References & Citations:

  [1]Yang W, et al. Novel Near-Infrared Fluorescence Probe for Bioimaging and Evaluating Superoxide Anion Fluctuations in Ferroptosis-Mediated Epilepsy. Anal Chem. 2023 Aug 22;95(33):12240-12246..

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported