NIR-FP

NIR-FP

• UNSPSC Description: NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O2-. O2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model[1].
• Target Antigen: Fluorescent Dye
• Type: Dye Reagents
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/nir-fp.html
• Solubility: 10 mM in DMSO
• Smiles: CC(CC(/C=C/C1=CC=C(OS(=O)(C(F)(F)F)=O)C=C1)=C/2)(C)CC2=C(C#N)\C#N
• Molecular Weight: 422.42
• References & Citations: [1]Yang W, et al. Novel Near-Infrared Fluorescence Probe for Bioimaging and Evaluating Superoxide Anion Fluctuations in Ferroptosis-Mediated Epilepsy. Anal Chem. 2023 Aug 22;95(33):12240-12246..
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported