NIR-FP

CAT: 0804-HY-149422Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149422Size:1 Each
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Description
NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O2-. O2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309) -induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A) -induced epilepsy model[1].
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nir-fp.html
Solubility
10 mM in DMSO
Smiles
CC(CC(/C=C/C1=CC=C(OS(=O)(C(F)(F)F)=O)C=C1)=C/2)(C)CC2=C(C#N)\C#N
Molecular Formula
C20H17F3N2O3S
Molecular Weight
422.42
References & Citations
[1]Yang W, et al. Novel Near-Infrared Fluorescence Probe for Bioimaging and Evaluating Superoxide Anion Fluctuations in Ferroptosis-Mediated Epilepsy. Anal Chem. 2023 Aug 22;95 (33) :12240-12246..
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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