NIR-FP

• Description :

  NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O2-. O2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309) -induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A) -induced epilepsy model[1].

• UNSPSC :

  12171500

• Target :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/nir-fp.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(CC(/C=C/C1=CC=C(OS(=O)(C(F)(F)F)=O)C=C1)=C/2)(C)CC2=C(C#N)\C#N

• Molecular Formula :

  C20H17F3N2O3S

• Molecular Weight :

  422.42

• References & Citations :

  [1]Yang W, et al. Novel Near-Infrared Fluorescence Probe for Bioimaging and Evaluating Superoxide Anion Fluctuations in Ferroptosis-Mediated Epilepsy. Anal Chem. 2023 Aug 22;95 (33) :12240-12246..

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported