FP-20 (sodium)

• Description:

  FP-20 sodium, a selective TLR4 agonist, is a vaccine adjuvant. FP-20 sodium induces MAPK- and NLRP3-dependent inflammasome activation. FP20 shows no toxicity in mouse vaccination experiments with OVA antigen and induces IgG production[1].

• UNSPSC:

  12352005

• Target:

  Toll-like Receptor (TLR)

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  CCCCCCCCCCCC(N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC(CCCCCCCCCCC)=O)CO)OP(O)(O[Na])=O)OC(CCCCCCCCCCC)=O)=O

• Molecular Formula:

  C42H79NNaO11P

• Molecular Weight:

  828.04

• References & Citations:

  [1]Alessio Romerio, et al. New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants. J Med Chem. 2023 Feb 23;66 (4) :3010-3029.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [3056013-47-6]