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FP-20 (sodium)

CAT: 0804-HY-N16024Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N16024Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FP-20 sodium, a selective TLR4 agonist, is a vaccine adjuvant. FP-20 sodium induces MAPK- and NLRP3-dependent inflammasome activation. FP20 shows no toxicity in mouse vaccination experiments with OVA antigen and induces IgG production[1].
CAS Number
3056013-47-6
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
CCCCCCCCCCCC(N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC(CCCCCCCCCCC)=O)CO)OP(O)(O[Na])=O)OC(CCCCCCCCCCC)=O)=O
Molecular Formula
C42H79NNaO11P
Molecular Weight
828.04
References & Citations
[1]Alessio Romerio, et al. New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants. J Med Chem. 2023 Feb 23;66 (4) :3010-3029.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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