Lysine-methotrexate

CAT: 0804-HY-149200Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149200Size:1 Each
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Description
Lysine-methotrexate, an analogue of Methotrexate (HY-14519), is a dihydrofolate reductase (DHFR) inhibitor[1].
CAS Number
[80407-56-3]
UNSPSC
12352005
Target
Antifolate
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lysine-methotrexate.html
Solubility
10 mM in DMSO
Smiles
NC1=NC(N)=NC2=C1N=C(CN(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCCCN)=O)C)C=N2
Molecular Formula
C21H27N9O3
Molecular Weight
453.50
References & Citations
[1]Kempton RJ, et al. Lysine and ornithine analogues of methotrexate as inhibitors of dihydrofolate reductase. J Med Chem. 1982 Apr;25 (4) :475-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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