Lysine-methotrexate
CAT:
804-HY-149200
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Lysine-methotrexate
- CAS Number: 80407-56-3
- UNSPSC Description: Lysine-methotrexate, an analogue of Methotrexate (HY-14519), is a dihydrofolate reductase (DHFR) inhibitor[1].
- Target Antigen: Antifolate
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: COVID-19-anti-virus
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/lysine-methotrexate.html
- Solubility: 10 mM in DMSO
- Smiles: NC1=NC(N)=NC2=C1N=C(CN(C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCCCN)=O)C)C=N2
- Molecular Weight: 453.50
- References & Citations: [1]Kempton RJ, et al. Lysine and ornithine analogues of methotrexate as inhibitors of dihydrofolate reductase. J Med Chem. 1982 Apr;25(4):475-7.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported