Products for Research Use Only
RegisterLogin

PF-4348235

CAT: 0804-HY-148525Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-148525Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
β2AR/M-receptor agonist-2 (compound 15) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA) . β2AR/M-receptor agonist-2 shows potency to β2 adrenoceptor with an EC50 value of 3.7 nM. β2AR/M-receptor agonist-2 also has potency to human cloned M3 receptor with a Ki value of 0.73 nM. β2AR/M-receptor agonist-2 is a potent bronchodilator, it can be used for the research of chronic obstructive pulmonary disease (COPD) [1].
CAS Number
1017857-38-3
Product Name Alternative
β2AR/M-receptor agonist-2
UNSPSC
12352005
Target
Adrenergic Receptor; mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pf-4348235.html
Solubility
10 mM in DMSO
Smiles
O[C@H](C1=CC(NS(C)(=O)=O)=C(C=C1)O)CNCCCCCCCCCN(CC2)CCC2OC(NC3=C(C4=CC(Cl)=C(C=C4)O)C=CC=C3)=O
Molecular Formula
C36H49ClN4O7S
Molecular Weight
717.31
References & Citations
[1]Laura Hilton, et al. Optimized glucuronidation of dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD. MedChemComm. 2011.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P991635PF-07329640
HY-P990645-01PF-03732010
HY-171821-01PF-08046054
HY-108339-01PF-06471553
HY-101450-01PF-6274484
HY-120823-01PF-05381941
HY-13344-01PF-8380
HY-117885PF-5177624
HY-169092-01PF-07957472
HY-159657-01PF-07899895

Alternative Products

CatalogName
BUP21753PF-4348235 HCl
T72226L1-01PF-4348235 2HCl
MBS579460PF-03084014 (PF-3084014)
BA5950-5.1PF-06928215
BA7028-5PF-4840154
B5563-10PF 5081090
BA8315-10PF-06747711
C4756-10PF-622
A4689-10PF-06409577
BA1871-5.1PF-4878691

Popular Products