COX-2-IN-24

COX-2-IN-24

• CAS Number: 2417995-10-7
• UNSPSC Description: COX-2-IN-24 is an orally active inhibitor of COX-2 with IC50 value of 0.17 μM, shows anti-inflammatory and low ulcerogenic activities.
• Target Antigen: COX
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/cox-2-in-24.html
• Solubility: 10 mM in DMSO
• Smiles: O=S(C1=CC(C(N2C3=CC=C(Br)C=C3)=NNC2=S)=CC(NCCCC)=C1OC4=CC=CC=C4)(N)=O
• Molecular Weight: 574.51
• References & Citations: [1]Tarek S Ibrahim, et al. Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold. Bioorg Chem. 2020 Jul;100:103878.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported