Apoptotic agent-2

Apoptotic agent-2

• CAS Number: 2482310-18-7
• UNSPSC Description: Apoptotic agent-2 (compound 14b) induces apoptosis by down-regulation of Bcl-2 and up-regulation of Bax and caspase-3. Apoptotic agent-2 exhibits anti-proliferative activities and can be used for cancer research[1].
• Target Antigen: Apoptosis; Bcl-2 Family; Caspase
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/apoptotic-agent-2.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=C(/N=N/C2=CC=C(Cl)C=C2)SC(N/N=C3C4=C(C5=NC6=CC=CC=C6N=C5\3)C=CC=C4)=N1
• Molecular Weight: 481.96
• References & Citations: [1]Fayed EA, et al. In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies. Bioorg Chem. 2020 Jul;100:103951.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported