Antihypertensive agent 2

• Description :

  Antihypertensive agent 2 (Compound 4g) is an antihypertensive agent. Antihypertensive agent 2 has effective antagonistic activities against angiotensin II receptor 1. Antihypertensive agent 2 reduces the blood pressure with equal or more potency compared to Losartan (HY-17512) [1].

• CAS Number :

  [9007-83-4]

• UNSPSC :

  12352005

• Target :

  Angiotensin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/antihypertensive-agent-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)C1=C(C2=CC=CC=C2)N(C(C3=CC=CC=C3)=O)C4=CC=CC=C41

• Molecular Formula :

  C22H15NO3

• Molecular Weight :

  341.36

• References & Citations :

  [1]Danilenko AV, et al. Design, synthesis and biological evaluation of novel indole-3-carboxylic acid derivatives with antihypertensive activity. Bioorg Med Chem Lett. 2023 Jun 15;90:129349.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported