Apoptotic agent-1

Apoptotic agent-1

• CAS Number: 2490538-26-4
• UNSPSC Description: Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].
• Target Antigen: Apoptosis
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/apoptotic-agent-1.html
• Solubility: 10 mM in DMSO
• Smiles: SC1=NC(C2=CC=C([N+]([O-])=O)C=C2)=C3C(N=CN=C3Cl)=N1
• Molecular Weight: 319.73
• References & Citations: [1]Haffez H, et al. Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity. Bioorg Chem. 2020 Nov;104:104249.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported