Apoptotic agent-1

• UNSPSC Description:

  Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/apoptotic-agent-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  SC1=NC(C2=CC=C([N+]([O-])=O)C=C2)=C3C(N=CN=C3Cl)=N1

• Molecular Weight:

  319.73

• References & Citations:

  [1]Haffez H, et al. Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity. Bioorg Chem. 2020 Nov;104:104249.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2490538-26-4