Apoptotic agent-3

• Description :

  Apoptotic agent-3 (compound 15f) promotes apoptosis through the potential mitochondria-mediated Bcl-2/Bax pathway and activation of the Caspase 3 pathway. Apoptotic agent-3 exhibits anti-proliferative activities and can be used for cancer research[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Bcl-2 Family; Caspase

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/apoptotic-agent-3.html

• Purity :

  98.19

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=CC=C(C2=CS/C(N2C3=CC=CC=C3)=N/N=C4C5=C(C6=NC7=CC=CC=C7N=C6\4)C=CC=C5)C=C1

• Molecular Formula :

  C31H21N5OS

• Molecular Weight :

  511.60

• References & Citations :

  [1]Fayed EA, et al. In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies. Bioorg Chem. 2020 Jul;100:103951.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Bax; Bcl-2; Caspase 3

• CAS Number :

  [2482310-23-4]