DC-CPin711

• Description:

  DC-CPin711 is a potent and selective inhibitor of CREB-binding protein (CBP) bromodomain with an IC50 of 0.0626 μM. DC-CPin711 arrests cell cycle at G1 phase and induces apoptosis[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dc-cpin711.html

• Purity:

  99.09

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1CCCC2=C1C=C(NC(C3=CC=CC(C4=CC=NC=C4)=C3)=O)C=C2)NC

• Molecular Formula:

  C23H22N4O2

• Molecular Weight:

  386.45

• References & Citations:

  [1]Chen Y, et al. Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain. Bioorg Chem. 2020 Aug;101:103991.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2447559-21-7]