DC-CPin711

CAT: 0804-HY-147868-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-147868-01Size:5 mg
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Description
DC-CPin711 is a potent and selective inhibitor of CREB-binding protein (CBP) bromodomain with an IC50 of 0.0626 μM. DC-CPin711 arrests cell cycle at G1 phase and induces apoptosis[1].
CAS Number
[2447559-21-7]
UNSPSC
12352005
Target
Apoptosis; Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dc-cpin711.html
Purity
99.09
Solubility
10 mM in DMSO
Smiles
O=C(N1CCCC2=C1C=C(NC(C3=CC=CC(C4=CC=NC=C4)=C3)=O)C=C2)NC
Molecular Formula
C23H22N4O2
Molecular Weight
386.45
References & Citations
[1]Chen Y, et al. Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain. Bioorg Chem. 2020 Aug;101:103991.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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