CDK7-IN-18

• Description :

  CDK7-IN-18 is a potent inhibitor of CDK7. CDK7-IN-18 is a pyrimidinyl derivative compound. CDK7-IN-18 has the potential for the research of various cancers, especially the cancer with transcriptional dysregulation (extracted from patent CN114249712A, compound 15) [1].

• UNSPSC :

  12352005

• Target :

  CDK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cdk7-in-18.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1(CC[C@@H](CN1)NC2=NC=C(C(C3=CNC4=C(C=CC=C34)S(C)(=O)=NC#N)=N2)C(F)(F)F)C

• Molecular Formula :

  C22H24F3N7OS

• Molecular Weight :

  491.53

• References & Citations :

  [1]Guanpeng Qiu, et al. Pyrimidinyl derivatives, method for the production thereof and use thereof. Patent CN114249712A.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2765676-81-9]