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CDK7-IN-6

CAT: 0804-HY-145394Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145394Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer[1].
CAS Number
2378710-04-2
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk7-in-6.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=CC(N2N=C(C(C)(C)O)C=C2)=C1CNC3=NC(N4CCC(CC4)N)=NC5=C(C(C)C)C=NN35
Molecular Formula
C26H34ClN9O
Molecular Weight
524.06
References & Citations
[1]Kiyean NAM, et al.Preparation of pyrazolotriazine and/or pyrazolopyrimidine derivatives as selective inhibitor of cyclin dependent kinase. WO2019197549 A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7

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