CDK7-IN-12

• Description :

  CDK7-IN-12 is a potent inhibitor of CDK7. CDK7-IN-12 plays a key role in transcriptional regulation and cell cycle regulation. CDK7-IN-12 effectively inhibit malignant tumor proliferation in vitro and in vivo. CDK7-IN-12 has the potential for the research of cancer disease (extracted from patent WO2021249417A1, compound 43) [1].

• UNSPSC :

  12352005

• Target :

  CDK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cdk7-in-12.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC(C1=C(C2=CNC3=C2C=CC=C3)N=C(N[C@@H]4CNCCC4)C5=NC=CN51)(F)F

• Molecular Formula :

  C20H19F3N6

• Molecular Weight :

  400.40

• References & Citations :

  [1]Jing Wang, et al. Heterocyclic compounds and their derivatives. Patent WO2021249417A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2750638-94-7]