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CDK7-IN-10

CAT: 0804-HY-145424Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145424Size:1 Each
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Description
CDK7-IN-10 is a CDK7 inhibitor with an IC50 of less than 100 nM, extracted from patent WO2021016388A1, compound I-1. CDK7-IN-10 is useful in inhibiting the activity of a kinase. CDK7-IN-10 has the potential of inhibiting cell growth and inducing cell apoptosis[1].
CAS Number
2588110-62-5
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cdk7-in-10.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C=C1)NC(C=C)=O)NC2=NN(C)C3=C2CN(C(N[C@@H](C4=CC=CC=C4)CN(C)C)=O)C3(C)C
Molecular Formula
C29H35N7O3
Molecular Weight
529.63
References & Citations
[1]Tinghu Zhang, et al. Inhibitors of cyclin-dependent kinase 7 and uses thereof. WO2021016388A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7

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