CDK7-IN-10

CDK7-IN-10

• CAS Number: 2588110-62-5
• UNSPSC Description: CDK7-IN-10 is a CDK7 inhibitor with an IC50 of less than 100 nM, extracted from patent WO2021016388A1, compound I-1. CDK7-IN-10 is useful in inhibiting the activity of a kinase. CDK7-IN-10 has the potential of inhibiting cell growth and inducing cell apoptosis[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/cdk7-in-10.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=C(C=C1)NC(C=C)=O)NC2=NN(C)C3=C2CN(C(N[C@@H](C4=CC=CC=C4)CN(C)C)=O)C3(C)C
• Molecular Weight: 529.63
• References & Citations: [1]Tinghu Zhang, et al. Inhibitors of cyclin-dependent kinase 7 and uses thereof. WO2021016388A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported