CDK7-IN-10

• UNSPSC Description:

  CDK7-IN-10 is a CDK7 inhibitor with an IC50 of less than 100 nM, extracted from patent WO2021016388A1, compound I-1. CDK7-IN-10 is useful in inhibiting the activity of a kinase. CDK7-IN-10 has the potential of inhibiting cell growth and inducing cell apoptosis[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/cdk7-in-10.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(C=C1)NC(C=C)=O)NC2=NN(C)C3=C2CN(C(N[C@@H](C4=CC=CC=C4)CN(C)C)=O)C3(C)C

• Molecular Weight:

  529.63

• References & Citations:

  [1]Tinghu Zhang, et al. Inhibitors of cyclin-dependent kinase 7 and uses thereof. WO2021016388A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2588110-62-5