CDK7-IN-10

• Description :

  CDK7-IN-10 is a CDK7 inhibitor with an IC50 of less than 100 nM, extracted from patent WO2021016388A1, compound I-1. CDK7-IN-10 is useful in inhibiting the activity of a kinase. CDK7-IN-10 has the potential of inhibiting cell growth and inducing cell apoptosis[1].

• UNSPSC :

  12352005

• Target :

  CDK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/cdk7-in-10.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC=C(C=C1)NC(C=C)=O)NC2=NN(C)C3=C2CN(C(N[C@@H](C4=CC=CC=C4)CN(C)C)=O)C3(C)C

• Molecular Formula :

  C29H35N7O3

• Molecular Weight :

  529.63

• References & Citations :

  [1]Tinghu Zhang, et al. Inhibitors of cyclin-dependent kinase 7 and uses thereof. WO2021016388A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CDK7

• CAS Number :

  [2588110-62-5]