CDK7-IN-8

• UNSPSC Description:

  CDK7-IN-8 is a potent CDK7 inhibitor with IC50 of 54.29 nM. CDK7-IN-8 has inhibitory effect on certain cancer cells and in vivo tumor models[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk7-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=C2N(N=C1)C(NC3CCN(CC3)C(O[C@@H]4CN(CC4)C(/C=C/CN(C)C)=O)=O)=NC(C)=N2)C

• Molecular Weight:

  498.62

• References & Citations:

  [1]Hu Yonghan, et al. Heterocyclic compound, and pharmaceutical composition thereof, preparation method therefor, intermediate thereof and application thereof. WO2021121390

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2654003-64-0