CDK7-IN-8

CDK7-IN-8

• CAS Number: 2654003-64-0
• UNSPSC Description: CDK7-IN-8 is a potent CDK7 inhibitor with IC50 of 54.29 nM. CDK7-IN-8 has inhibitory effect on certain cancer cells and in vivo tumor models[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cdk7-in-8.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C1=C2N(N=C1)C(NC3CCN(CC3)C(O[C@@H]4CN(CC4)C(/C=C/CN(C)C)=O)=O)=NC(C)=N2)C
• Molecular Weight: 498.62
• References & Citations: [1]Hu Yonghan, et al. Heterocyclic compound, and pharmaceutical composition thereof, preparation method therefor, intermediate thereof and application thereof. WO2021121390
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported