CDK7-IN-16

• Description:

  CDK7-IN-16 (compound 9) is a potent CDK 7 inhibitor with an IC50 range of 1 ~ 10 nM. CDK7-IN-16 can be used for researching anticancer, especially the cancer with transcriptional dysregulation[1].

• UNSPSC:

  12352005

• Target:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk7-in-16.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CS(=O)(NC1=C2NC=C(C2=CC=C1)C3=C(C=NC(N[C@H]4CCCNC4)=N3)C(F)(F)F)=O

• Molecular Formula:

  C19H21F3N6O2S

• Molecular Weight:

  454.47

• References & Citations:

  [1]Pengguan Qiu, et al. Pyrimidinyl derivatives, method for the production thereof and use thereof. CN114249712A (compound 9)

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CDK7

• CAS Number:

  [2765676-32-0]