CDK7-IN-33

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  CDK7-IN-33 (Compound 148) is a CDK7 inhibitor with a Ki value of 21.75 nM. It suppresses the proliferation of A549 cells expressing CDK7WT, with a pIC50 of 7.37.

• Smiles:

  C[C@@H]1C2=C (N=CN=C2NC=3C (O1) =C (C) C=C (C3) C4CCN (CC4) C5CN (C (C#CC) =O) C5) N6CCS (=O) (=O) CC6

• Molecular Formula:

  C29H36N6O4S

• Molecular Weight:

  564.699

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2796279-20-2