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NLRP3 agonist 3

CAT: 0804-HY-176452Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176452Size:1 Each
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Description
NLRP3 agonist 3 (Compound Payload 5) is an antibody-drug conjugate (ADC) . NLRP3 agonist 3 is a NLRP3 agonist that induces IL-1β secretion in primary human monocytes. NLRP3 agonist 3 can be used in cancer research[1].
UNSPSC
12352005
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
NC1=NC2=CC(C3=CC=NN3)=CC=C2C(N[C@H]4CC[C@H](OC([C@@H](NC([C@@H](N)C(C)C)=O)CCCNC(N)=O)=O)C4)=C1
Molecular Formula
C28H39N9O4
Molecular Weight
565.67
References & Citations
[1]Riehl PS, et al. Antibody-Drug Conjugates of NLRP3 Agonists: How Overcoming Lysosomal Accumulation Necessitated Noncanonical Linker Attachments. J Med Chem. 2025 May 8;68 (9) :9799-9810.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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