Cyclic HPMPC
CAT:
804-HY-147014
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cyclic HPMPC
- CAS Number: 127757-45-3
- UNSPSC Description: Cyclic HPMPC is a potent antiviral agent. Cyclic HPMPC can increase arterial oxygen saturation levels in lethal vaccinia virus (IHD strain)-infected mice. Cyclic HPMPC improves the outcome of congenital guinea pig cytomegalovirus (GPCMV) infection and decreases viral replication in guinea pig model[1][2].
- Target Antigen: CMV; Orthopoxvirus
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/cyclic-hpmpc.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1N(C=CC(N)=N1)C[C@H](OC2)CO[P]2(O)=O
- Molecular Weight: 261.17
- References & Citations: [1]Smee DF, et al. Effects of four antiviral substances on lethal vaccinia virus (IHD strain) respiratory infections in mice. Int J Antimicrob Agents. 2004;23(5):430-437.|[2]Bravo FJ, et al. Effect of maternal treatment with cyclic HPMPC in the guinea pig model of congenital cytomegalovirus infection. J Infect Dis. 2006;193(4):591-597.
- Shipping Conditions: Room temperature
- Clinical Information: Phase 1