Cyclic tri-AMP

CAT: 0804-HY-137721Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-137721Size:1 Each
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Description
Cyclic tri-AMP is a component of the cyclic oligonucleotide-based anti-phage signaling system (CBASS), and acts as the second messenger in the immune response against viral infection. Cyclic tri-AMP binds to and activates DNA endonuclease NucC, results in cell death and exhibits antiviral activity[1].
CAS Number
[54447-85-7]
UNSPSC
12352005
Target
Endonuclease
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyclic-tri-amp.html
Smiles
O[C@H]1[C@](O[C@@](CO[P](O)(O[C@]2([H])[C@](CO3)([H])O[C@](N4C5=NC=NC(N)=C5N=C4)([H])[C@@H]2O)=O)([H])[C@@]1([H])O[P](O)(OC[C@](O[C@@]6([H])N7C8=NC=NC(N)=C8N=C7)([H])[C@](O[P]3(O)=O)([H])[C@H]6O)=O)([H])N9C%10=NC=NC(N)=C%10N=C9
Molecular Formula
C30H36N15O18P3
Molecular Weight
987.62
References & Citations
[1]Ko TP, et al., Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res. 2021 May 7;49 (8) :4725-4737.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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