Cyclic tri-AMP

• Description :

  Cyclic tri-AMP is a component of the cyclic oligonucleotide-based anti-phage signaling system (CBASS), and acts as the second messenger in the immune response against viral infection. Cyclic tri-AMP binds to and activates DNA endonuclease NucC, results in cell death and exhibits antiviral activity[1].

• CAS Number :

  [54447-85-7]

• UNSPSC :

  12352005

• Target :

  Endonuclease

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/cyclic-tri-amp.html

• Smiles :

  O[C@H]1[C@](O[C@@](CO[P](O)(O[C@]2([H])[C@](CO3)([H])O[C@](N4C5=NC=NC(N)=C5N=C4)([H])[C@@H]2O)=O)([H])[C@@]1([H])O[P](O)(OC[C@](O[C@@]6([H])N7C8=NC=NC(N)=C8N=C7)([H])[C@](O[P]3(O)=O)([H])[C@H]6O)=O)([H])N9C%10=NC=NC(N)=C%10N=C9

• Molecular Formula :

  C30H36N15O18P3

• Molecular Weight :

  987.62

• References & Citations :

  [1]Ko TP, et al., Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res. 2021 May 7;49 (8) :4725-4737.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported