Cyclic GMP (Standard)

CAT: 0804-HY-113469R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-113469R-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Cyclic GMP (Standard) is the analytical standard of Cyclic GMP (HY-113469) . This product is intended for research and analytical applications. Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs) . Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses[1][2][3][4].
CAS Number
[7665-99-8]
UNSPSC
12352005
Target
Endogenous Metabolite; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology; Cardiovascular Disease
Purity
99.54
Smiles
O[C@@H]([C@H](N1C=NC2=C1N=C(N)NC2=O)O[C@@H]3CO4)[C@@H]3OP4(O)=O
Molecular Formula
C10H12N5O7P
Molecular Weight
345.21
References & Citations
[1]Wu J, et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science. 2013 Feb 15;339 (6121) :826-30.|[2]Ablasser A, et al. Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. Nature. 2013 Nov 28;503 (7477) :530-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

Related Products

CatalogName
HY-113469ARCyclic GMP (sodium) (Standard)
HY-113469-01Cyclic GMP
HY-107780Cyclic-di-GMP
HY-113469B-01Cyclic GMP (TBAOH)
HY-113469A-01Cyclic GMP (sodium)
HY-W767865Cyclic GMP (sodium) -13C5
HY-110382-01Cyclic-di-GMP (disodium)
HY-107780B-01Cyclic-di-GMP (diammonium)
HY-W654000Cyclic GMP-13C,15N2
HY-107780ACyclic-di-GMP (sodium)

Alternative Products

CatalogName
C080-70ULCyclic GMP Standard, 70UL
C066-625ULCyclic AMP Standard, 625UL
C080-625ULCyclic GMP Standard, 625UL
C080-125ULCyclic GMP Standard, 125UL
C080-350ULCyclic GMP Standard, 350UL
C066-125ULCyclic AMP Standard, 125UL
MBS2098170-01General Cyclic Adenosine Monophosphate (cAMP) Antibody Pair Kit (with Standard)
MBS2099398-01Rat Cyclic ADP Ribose Hydrolase (cADPRH) Antibody Pair Kit (with Standard)
MBS2099396-01Human Cyclic ADP Ribose Hydrolase (cADPRH) Antibody Pair Kit (with Standard)
MBS2099397-01Mouse Cyclic ADP Ribose Hydrolase (cADPRH) Antibody Pair Kit (with Standard)

Popular Products