Products for Research Use Only
RegisterLogin

Cyclic GMP (Standard)

CAT: 0804-HY-113469R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-113469R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cyclic GMP (Standard) is the analytical standard of Cyclic GMP. This product is intended for research and analytical applications. Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses[1][2][3][4].
CAS Number
7665-99-8
UNSPSC
12352005
Target
Endogenous Metabolite; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology; Cardiovascular Disease
Purity
99.54
Smiles
O[C@@H]([C@H](N1C=NC2=C1N=C(N)NC2=O)O[C@@H]3CO4)[C@@H]3OP4(O)=O
Molecular Formula
C10H12N5O7P
Molecular Weight
345.21
References & Citations
[1]Wu J, et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science. 2013 Feb 15;339 (6121) :826-30.|[2]Ablasser A, et al. Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. Nature. 2013 Nov 28;503 (7477) :530-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

Related Products

CatalogName
HY-113469ARCyclic GMP (sodium) (Standard)
HY-113469-01Cyclic GMP
HY-113469B-01Cyclic GMP (TBAOH)
HY-113469A-01Cyclic GMP (sodium)
HY-107780Cyclic-di-GMP
HY-W767865Cyclic GMP (sodium) -13C5
HY-107780B-01Cyclic-di-GMP (diammonium)
HY-110382-01Cyclic-di-GMP (disodium)
HY-107780ACyclic-di-GMP (sodium)
HY-W654000Cyclic GMP-13C,15N2

Alternative Products

CatalogName
C080-70ULCyclic GMP Standard, 70UL
C080-125ULCyclic GMP Standard, 125UL
C080-625ULCyclic GMP Standard, 625UL
C066-625ULCyclic AMP Standard, 625UL
C066-125ULCyclic AMP Standard, 125UL
C080-350ULCyclic GMP Standard, 350UL
MBS2098170-01General Cyclic Adenosine Monophosphate (cAMP) Antibody Pair Kit (with Standard)
MBS2099398-01Rat Cyclic ADP Ribose Hydrolase (cADPRH) Antibody Pair Kit (with Standard)
MBS2099397-01Mouse Cyclic ADP Ribose Hydrolase (cADPRH) Antibody Pair Kit (with Standard)
MBS2099396-01Human Cyclic ADP Ribose Hydrolase (cADPRH) Antibody Pair Kit (with Standard)

Popular Products