RegisterLogin

PRMT4-IN-1

CAT: 0804-HY-146810Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-146810Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PRMT4-IN-1 is a selective inhibitor of PRMT4 (IC50=3.2 nM) . PRMT4-IN-1 inhibits MCF7 relative viability[1].
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt4-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)C1=CC(O)=C2C=C(NC(NCCCCNC(NC/C=C/[C@H]3O[C@@H](N4C=NC5=C(N)N=CN=C45)[C@H](O)[C@@H]3O)=N)=O)C=CC2=C1
Molecular Formula
C30H36N10O7
Molecular Weight
648.67
References & Citations
[1]Iannelli G, et al. Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach. J Med Chem. 2022 Sep 8;65 (17) :11574-11606.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT1; PRMT3; PRMT4; PRMT5; PRMT6; PRMT7; PRMT8

Related Products

CatalogName
HY-155154APRMT4-IN-3
HY-155154PRMT4-IN-2
HY-126256PRMT5-IN-1
HY-115758-01PRMT1-IN-1
HY-147185-01PRMT7-IN-1
HY-W280124-01PRMT9-IN-1
HY-173092PRMT5 ligand 1
HY-126256A-01PRMT5-IN-1 (hydrochloride)
HY-163799PRMT5-MTA-IN-1
HY-163434PRMT5/EGFR-IN-1

Alternative Products

CatalogName
T68378-01PRMT4-IN-1
MBS5823051PRMT4-IN-2
MBS5821017PRMT4-IN-3
ASA-B1567PRMT4 Antibody
E24033PRMT4 Protein
MBS515601-01PRMT4, Active
403843-01PRMT4 discontinued
YF-PA25595anti-PRMT4
MBS8505337-01PRMT4/CARM1 Antibody
V4583SAF-100UGCARM1 Antibody / PRMT4

Popular Products