PRMT4-IN-3

• Description :

  PRMT4-IN-3 (compound 56) is a potent inhibitor of class I protein arginine methyltransferase (PRMT), targeting PRMT4 (IC50: 37 nM) and PRMT4 (IC50: 253 nM) [1].

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/prmt4-in-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N[C@H]1CN(CCNC)CC1)C2=CC3=NC=NC(NC4=CC=C(CN)C=C4)=C3C=C2

• Molecular Formula :

  C23H29N7O

• Molecular Weight :

  419.52

• References & Citations :

  [1]Bhattacharya D, et al. Development of selective class I protein arginine methyltransferase inhibitors through fragment-based drug design approach. Eur J Med Chem. 2023 Nov 15;260:115713..

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported