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PRMT4-IN-3

CAT: 0804-HY-155154ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155154ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PRMT4-IN-3 (compound 56) is a potent inhibitor of class I protein arginine methyltransferase (PRMT), targeting PRMT4 (IC50: 37 nM) and PRMT4 (IC50: 253 nM) [1].
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt4-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H]1CN(CCNC)CC1)C2=CC3=NC=NC(NC4=CC=C(CN)C=C4)=C3C=C2
Molecular Formula
C23H29N7O
Molecular Weight
419.52
References & Citations
[1]Bhattacharya D, et al. Development of selective class I protein arginine methyltransferase inhibitors through fragment-based drug design approach. Eur J Med Chem. 2023 Nov 15;260:115713..
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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