SDR-04

CAT: 0804-HY-146741Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-146741Size:1 Each

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Description

SDR-04 is a BET inhibitor and exhibits strong BRD4-BD1 affinity and inhibition activity. SDR-04 potently suppresses MV4;11 cancer cell line proliferation[1].

CAS Number

879593-54-1

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sdr-04.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(C2=C(N3C=CN=CC3=N2)NC4=CC=CC=C4)=CC=C1O

Molecular Formula

C19H16N4O2

Molecular Weight

332.36

References & Citations

[1]Ru Dong, et al. Design, synthesis and anticancer evaluation of 3-methyl-1H-indazole derivatives as novel selective bromodomain-containing protein 4 inhibitors. Bioorg Med Chem. 2021 Dec 29;55:116592.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

BD1

Chemical Information

2-Methoxy-4-(3-phenylimino-1,7-dihydroimidazo[1,2-a]pyrazin-2-ylidene)-1-cyclohexa-2,5-dienone

2-methoxy-4-(3-phenylimino-1,7-dihydroimidazo[1,2-a]pyrazin-2-ylidene)-1-cyclohexa-2,5-dienone is a member of quinomethanes.

CAS Number	879593-54-1
PubChem CID	5309317
IUPAC Name	4-(3-anilinoimidazo[1,2-a]pyrazin-2-yl)-2-methoxyphenol
Molecular Formula	C19H16N4O2
Molecular Weight	332.4
XLogP	3.8
Topological Polar Surface Area	71.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Heavy Atom Count	25
Formal Charge	0
Complexity	432

SMILES

COC1=C(C=CC(=C1)C2=C(N3C=CN=CC3=N2)NC4=CC=CC=C4)O

InChI

InChI=1S/C19H16N4O2/c1-25-16-11-13(7-8-15(16)24)18-19(21-14-5-3-2-4-6-14)23-10-9-20-12-17(23)22-18/h2-12,21,24H,1H3

InChIKey

KZMVPUIBSUVYJZ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 879593-54-1

CID: 5309317

Formula: C19H16N4O2

MW: 332.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	332.4
XLogP3	3.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	332.12732577
Monoisotopic Mass	332.12732577
Topological Polar Surface Area	71.7 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	432
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-13953-01	JIB-04
HY-156290	SAP-04
HY-28325	AMC-04
HY-179621	EQ-04
HY-172162-01	LC-04-045
HY-136252-01	BSJ-04-132
HY-174282-01	RDS-04-010
HY-107842-01	(Z) -JIB-04
HY-115805	YKL-04-085
HY-152185-01	BSJ-04-122

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575826-01	SDR (Biotin)
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GTR17918245-01	SDR Antibody (HRP)
GTR18181512	SDR O Antibody
GTR18325978-01	SDR Antibody (Center)

SDR-04

Chemical Information

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