SDR-04

• UNSPSC Description:

  SDR-04 is a BET inhibitor and exhibits strong BRD4-BD1 affinity and inhibition activity. SDR-04 potently suppresses MV4;11 cancer cell line proliferation[1].

• Target Antigen:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sdr-04.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC(C2=C(N3C=CN=CC3=N2)NC4=CC=CC=C4)=CC=C1O

• Molecular Weight:

  332.36

• References & Citations:

  [1]Ru Dong, et al. Design, synthesis and anticancer evaluation of 3-methyl-1H-indazole derivatives as novel selective bromodomain-containing protein 4 inhibitors. Bioorg Med Chem. 2021 Dec 29;55:116592.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  879593-54-1