SDR-04

• Description :

  SDR-04 is a BET inhibitor and exhibits strong BRD4-BD1 affinity and inhibition activity. SDR-04 potently suppresses MV4;11 cancer cell line proliferation[1].

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/sdr-04.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=CC(C2=C(N3C=CN=CC3=N2)NC4=CC=CC=C4)=CC=C1O

• Molecular Formula :

  C19H16N4O2

• Molecular Weight :

  332.36

• References & Citations :

  [1]Ru Dong, et al. Design, synthesis and anticancer evaluation of 3-methyl-1H-indazole derivatives as novel selective bromodomain-containing protein 4 inhibitors. Bioorg Med Chem. 2021 Dec 29;55:116592.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  BD1

• CAS Number :

  [879593-54-1]