AMC-04

• Description :

  AMC-04 is an unfolded protein response (UPR) activator, which activates UPR pathway through ROS and p38 MAPK signaling and induces apoptotic cell death. AMC-04 can be used for cancer research[1].

• UNSPSC :

  12352005

• Target :

  P38 MAPK; Reactive Oxygen Species (ROS)

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/amc-04.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N1CCN(CC2=CC(OC)=CC=C2OC)CC1)C3=CC=C(C4=CC=CC=C4)C=C3

• Molecular Formula :

  C26H28N2O3

• Molecular Weight :

  416.51

• References & Citations :

  [1]Kim SY, et al. Molecular mechanisms underlying the effects of the small molecule AMC-04 on apoptosis: Roles of the activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway. Chem Biol Interact. 2020 Dec 1;332:109277.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [792928-94-0]