PPARγ agonist 1

• Description :

  PPARγ agonist 1 (compound 15) is a potent agonist of PPARγ. PPARγ agonist 1 shows high efficacy to activate hPPARγ without raising a full agonism and probably avoiding adverse effects. PPARγ agonist 1 has the potential for the research of cardiovascular diseases associated with metabolic disorders[1].

• UNSPSC :

  12352005

• Target :

  PPAR

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/pparγ-agonist-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C/C(CC/C=C(C(NC1=CC=CC=C1)=O)\C)=C\CCC2(CCC3=C(O2)C=CC(OCC4=CC=CC=C4)=C3)C

• Molecular Formula :

  C34H39NO3

• Molecular Weight :

  509.68

• References & Citations :

  [1]Vila L, et al. Synthesis and biological studies of "Polycerasoidol" and "trans-δ-Tocotrienolic acid" derivatives as PPARα and/or PPARγ agonists. Bioorg Med Chem. 2022;53:116532.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3032632-09-7]