PPARγ agonist 1

• Description:

  PPARγ agonist 1 (compound 15) is a potent agonist of PPARγ. PPARγ agonist 1 shows high efficacy to activate hPPARγ without raising a full agonism and probably avoiding adverse effects. PPARγ agonist 1 has the potential for the research of cardiovascular diseases associated with metabolic disorders[1].

• UNSPSC:

  12352005

• Target:

  PPAR

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/pparγ-agonist-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C/C(CC/C=C(C(NC1=CC=CC=C1)=O)\C)=C\CCC2(CCC3=C(O2)C=CC(OCC4=CC=CC=C4)=C3)C

• Molecular Formula:

  C34H39NO3

• Molecular Weight:

  509.68

• References & Citations:

  [1]Vila L, et al. Synthesis and biological studies of "Polycerasoidol" and "trans-δ-Tocotrienolic acid" derivatives as PPARα and/or PPARγ agonists. Bioorg Med Chem. 2022;53:116532.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3032632-09-7]