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C-ABL-IN-4

CAT: 0804-HY-146530Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146530Size:1 Each
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Description
C-ABL-IN-4 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-4 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 54) [1].
CAS Number
2626934-68-5
UNSPSC
12352005
Target
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/c-abl-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(C(C=C1)=O)C2=CN=CC(F)=C2)NC3=CC=C(C=C3)OC(F)(Cl)F
Molecular Formula
C18H11ClF3N3O3
Molecular Weight
409.75
References & Citations
[1] Michael J. RAWLING, et al. New compounds and methods. Patent WO2021048567A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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