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AMPK activator 6

CAT: 0804-HY-146398Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146398Size:1 Each
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Description
AMPK activator 6 (Compound GC) reduces lipid content and activates the AMPK pathway in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase in triglyceride (TG), total cholesterol (TC), low-density lipoprotein-C (LDL-C), and other biochemical indices in blood serum. AMPK activator 6 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome[1].
CAS Number
189299-03-4
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ampk-activator-6.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C\CC/C(C)=C\CC1=C(C=C(C(C(/C=C/C2=CC=C(C=C2)O)=O)=C1O)O)O
Molecular Formula
C25H28O5
Molecular Weight
408.49
References & Citations
[1]Mengdi Zhang, et al. Synthesis of natural 3'-Prenylchalconaringenin and biological evaluation of ameliorating non-alcoholic fatty liver disease and metabolic syndrome. Eur J Med Chem. 2020 Nov 1;205:112649.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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