AMPK activator 15

CAT: 0931-MF-0062779-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0062779-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
AMPK|||E1/E2/E3 Enzyme|||Mitochondrial Metabolism
Related Pathways
Ubiquitination|||PI3K/Akt/mTOR signaling|||Metabolism|||Chromatin/Epigenetic
Bioactivity
AP39 Prodrug 1 (Compound M1) is a mitochondria-targeted H2S prodrug. In hepatocytes, it induces ROS-dependent mild mitochondrial uncoupling, activates mitochondria-associated AMPK, and inhibits Palmitic acid (PA) -induced lipid accumulation.
Smiles
O=C1OC2=CC(OCC3=CC(OCCCC[P+](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)=CC=C3[N+]([O-])=O)=CC=C2C=C1COC(OC7=C(C(C)(C)CC(S)=O)C(C)=CC(C)=C7)=O.[Br-]
Molecular Formula
C53H51BrNO10PS
Molecular Weight
1004.92
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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