AMPK activator 15

• Target :

  AMPK|||E1/E2/E3 Enzyme|||Mitochondrial Metabolism

• Related Pathways :

  Ubiquitination|||PI3K/Akt/mTOR signaling|||Metabolism|||Chromatin/Epigenetic

• Bioactivity :

  AP39 Prodrug 1 (Compound M1) is a mitochondria-targeted H2S prodrug. In hepatocytes, it induces ROS-dependent mild mitochondrial uncoupling, activates mitochondria-associated AMPK, and inhibits Palmitic acid (PA) -induced lipid accumulation.

• Smiles :

  O=C1OC2=CC(OCC3=CC(OCCCC[P+](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)=CC=C3[N+]([O-])=O)=CC=C2C=C1COC(OC7=C(C(C)(C)CC(S)=O)C(C)=CC(C)=C7)=O.[Br-]

• Molecular Formula :

  C53H51BrNO10PS

• Molecular Weight :

  1004.92

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C