AMPK activator 2
CAT:
804-HY-130723
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AMPK activator 2
- CAS Number: 2410961-69-0
- UNSPSC Description: AMPK activator 2 (compound 7a), a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549)[1].
- Target Antigen: AMPK
- Type: Reference compound
- Related Pathways: Epigenetics;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/ampk-activator-2.html
- Solubility: 10 mM in DMSO
- Smiles: N=C(NC(NC1=CC=C(C(F)(F)F)C=C1)=N)NCC(C)C
- Molecular Weight: 301.31
- References & Citations: [1]Di Xiao, et al. Synthesis, biological evaluation and anti-proliferative mechanism of fluorine-containing proguanil derivatives. Bioorg Med Chem. 2020 Jan 15;28(2):115258.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported