LXR agonist 2

• UNSPSC Description:

  LXR agonist 2 (compound 18rr) is a potent LXR (liver X receptor) agonist. LXR agonist 2 can stabilize NCOA1 (co-activator), leading to LXR agonism[1].

• Target Antigen:

  LXR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/lxr-agonist-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC([C@H]1N(CC[C@]12C(N(C3=C2C=CC=C3)C4=CC=CC(C5=CC=C(C(Cl)=C5)C(N(C)C)=O)=C4)=O)C(CC(C)(C)C)=O)C

• Molecular Weight:

  586.16

• References & Citations:

  [1]Chen Z, et al. Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors. Eur J Med Chem. 2020 Nov 15;206:112793.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2978788-07-5