Products for Research Use Only
RegisterLogin

LSD1-IN-18

CAT: 0804-HY-146283Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-146283Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LSD1-IN-18 (compound 7) is a potent, non-covalent and selective LSD1 inhibitor, with Ki of 0.156 μM and KD of 0.075 μM, respectively. LSD1-IN-18 shows antiproliferative activity in THP-1 leukemia cells and MDA-MB-231 breast cancer cells, with IC50 (72 h) of 0.16 and 0.21 μM, respectively[1].
CAS Number
2983011-61-4
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lsd1-in-18.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(C(NC3CCN(CC3)CC4=CC=C5C=CC=CC5=C4)=NC(NCCCN(C)C)=N2)C=C1OC
Molecular Formula
C31H40N6O2
Molecular Weight
528.69
References & Citations
[1]Menna M, et al. Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models. Eur J Med Chem. 2022 Jul 5;237:114410.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1

Related Products

CatalogName
HY-178826LSD1-IN-45
HY-144758LSD1-IN-17
HY-161849LSD1-IN-31
HY-160191-01LSD1-IN-30
HY-163859LSD1-IN-33
HY-173123LSD1-IN-40
HY-172809LSD1-IN-42
HY-145861LSD1-IN-14
HY-168086LSD1-IN-35
HY-160183LSD1-IN-29

Alternative Products

CatalogName
T63716-01LSD1-IN-18
bs-60179C-01GSK-LSD1 --- LSD1 Inhibitor
bs-66045C-01LSD1-C76, LSD1 Inhibitor
MBS8565299-01LSD1
GTR18868076-01Human Protein LSD1 (LSD1) ELISA Kit
MBS1217282-01Recombinant Arabidopsis thaliana Protein LSD1 (LSD1)
BA4801-5.1LSD1-IN-24
BA4809-5LSD1-IN-27
Mab-605126LSD1/AOF2
T210222-01LSD1-IN-32

Popular Products