5-HT6/5-HT2A receptor ligand-1

• UNSPSC Description:

  5-HT6/5-HT2A receptor ligand-1 (compound 33) is a dual 5-HT6/5-HT2A receptor antagonist, with a Ki of 2 nM and 11 nM, respectively. 5-HT6/5-HT2A receptor ligand-1 has the potential for neurological and psychiatric disorders research[1].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-ht6-5-ht2a-receptor-ligand-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=CC=C(C2=CC=C(CNCCC3=CNC4=C3C=C(F)C=C4)O2)C=C1

• Molecular Weight:

  350.39

• References & Citations:

  [1]Staroń J, et, al. Virtual screening-driven discovery of dual 5-HT 6/5-HT 2A receptor ligands with pro-cognitive properties. Eur J Med Chem. 2020 Jan 1;185:111857.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2411088-07-6