5-HT2A receptor agonist-3

• UNSPSC Description:

  5-HT2A receptor agonist-3 is the most selective agonist for the human 5-HT2A receptor yet discovered, with a Ki of 2.5 nM, and with 124-fold selectivity for 5-HT2A over the structurally similar 5-HT2C receptor[1].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/5-ht2a-receptor-agonist-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C([C@H]2N[C@@H](CCC2)CC3=C(C=C(C(OC)=C3)Br)OC)C=CC=C1

• Molecular Weight:

  420.34

• References & Citations:

  [1]Juncosa JI Jr, et al. Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands. ACS Chem Neurosci. 2013;4(1):96-109.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1391499-52-7