5-HT6/5-HT2A receptor ligand-2
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804-HY-146077
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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5-HT6/5-HT2A receptor ligand-2
- CAS Number: 2411088-16-7
- UNSPSC Description: 5-HT6/5-HT2A receptor ligand-2 (compound 42) is a brain-penetrant dual 5-HT6/5-HT2A receptor antagonist, with a Ki of 25 nM and 32 nM, respectively. 5-HT6/5-HT2A receptor ligand-2 shows pro-cognitive properties[1].
- Target Antigen: 5-HT Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/5-ht6-5-ht2a-receptor-ligand-2.html
- Solubility: 10 mM in DMSO
- Smiles: OC1=CC=C(C2=CC=C(CNCCC3=CNC4=NC=C(F)C=C43)O2)C=C1
- Molecular Weight: 351.37
- References & Citations: [1]Staroń J, et, al. Virtual screening-driven discovery of dual 5-HT 6/5-HT 2A receptor ligands with pro-cognitive properties. Eur J Med Chem. 2020 Jan 1;185:111857.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported