PD-1/PD-L1-IN-36

• UNSPSC Description:

  PD-1/PD-L1-IN-36 (Compound 2k) is a PD-1/PD-L1 complex inhibitor (IC50: 15 nM). PD-1/PD-L1-IN-36 can be used for research of cancer immunotherapy[1].

• Target Antigen:

  PD-1/PD-L1

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pd-1-pd-l1-in-36.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@H]1N(CC2=CC=C(OCC3=C(Br)C(C4=CC=CC=C4)=CC=C3)C(Br)=C2)CCCC1)O

• Molecular Weight:

  559.29

• References & Citations:

  [1]Konieczny M, et al. Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint. J Med Chem. 2020 Oct 8;63(19):11271-11285.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2714327-65-6