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CP-628006

CAT: 0804-HY-145126Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145126Size:1 Each
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Description
CP-628006, a small molecule CFTR potentiator, restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR.
CAS Number
305822-08-6
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cp-628006.html
Solubility
10 mM in DMSO
Smiles
CC(N=CC=C1)=C1CNC(C2=CC=C(C(CC[C@]3([H])C[C@](O)(CC4)CCC(F)(F)F)=C2)[C@@]34CC5=CC=CC=C5)=O
Molecular Formula
C32H35F3N2O2
Molecular Weight
536.63
References & Citations
[1]Liu J, et al. A small molecule CFTR potentiator restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR. Br J Pharmacol. 2021 Oct 13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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