CP-628006

• Description :

  CP-628006, a small molecule CFTR potentiator, restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR.

• UNSPSC :

  12352005

• Target :

  CFTR

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/cp-628006.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(N=CC=C1)=C1CNC(C2=CC=C(C(CC[C@]3([H])C[C@](O)(CC4)CCC(F)(F)F)=C2)[C@@]34CC5=CC=CC=C5)=O

• Molecular Formula :

  C32H35F3N2O2

• Molecular Weight :

  536.63

• References & Citations :

  [1]Liu J, et al. A small molecule CFTR potentiator restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR. Br J Pharmacol. 2021 Oct 13.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [305822-08-6]