CP-628006

• UNSPSC Description:

  CP-628006, a small molecule CFTR potentiator, restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR.

• Target Antigen:

  CFTR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/cp-628006.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(N=CC=C1)=C1CNC(C2=CC=C(C(CC[C@]3([H])C[C@](O)(CC4)CCC(F)(F)F)=C2)[C@@]34CC5=CC=CC=C5)=O

• Molecular Weight:

  536.63

• References & Citations:

  [1]Liu J, et al. A small molecule CFTR potentiator restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR. Br J Pharmacol. 2021 Oct 13.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  305822-08-6