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LSD1-IN-15

CAT: 0804-HY-144756Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144756Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor. LSD1-IN-15 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.149, 0.028, and 0.327 μM, respectively. LSD1-IN-15 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 9.9 μM[1].
UNSPSC
12352005
Target
Histone Demethylase; Monoamine Oxidase
Type
Reference compound
Related Pathways
Epigenetics; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lsd1-in-15.html
Solubility
10 mM in DMSO
Smiles
NC1CC1C2=CC=C(C=C2)NC(C3=CC=CC(C4=CC=CC=C4)=C3)=O
Molecular Formula
C22H20N2O
Molecular Weight
328.41
References & Citations
[1]Fioravanti R, et al. Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :973-985.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1; MAO-A; MAO-B

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