P38 MAPK-IN-3

CAT: 0804-HY-144697Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144697Size:1 Each
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Description
P38 MAPK-IN-3 (Compound 2c) is a p38α MAPK inhibitor. p38 MAPK-IN-3 has antitumor activities and induces apoptosis and ROS[1].
UNSPSC
12352005
Target
Apoptosis; p38 MAPK; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p38-mapk-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C)C=C1)/C=C/C2=CC=C(OC3=CC=C(Br)C=C3)C=C2
Molecular Formula
C22H17BrO2
Molecular Weight
393.27
References & Citations
[1]Halim PA, et al. Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :189-201.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P38α

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