p38 MAPK-IN-3

• UNSPSC Description:

  p38 MAPK-IN-3 (Compound 2c) is a p38α MAPK inhibitor. p38 MAPK-IN-3 has antitumor activities and induces apoptosis and ROS[1].

• Target Antigen:

  Apoptosis; p38 MAPK; Reactive Oxygen Species

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Immunology/Inflammation;MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/p38-mapk-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(C)C=C1)/C=C/C2=CC=C(OC3=CC=C(Br)C=C3)C=C2

• Molecular Weight:

  393.27

• References & Citations:

  [1]Halim PA, et al. Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer. J Enzyme Inhib Med Chem. 2022 Dec;37(1):189-201.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported