P38-α MAPK-IN-4

CAT: 0804-HY-146032Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-146032Size:1 Each
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Description
P38-α MAPK-IN-4 (Compound 69) is a selective p38α MAPK inhibitor with an IC50 of 1.5 µM. p38-α MAPK-IN-4 rapidly and strongly prevents the development of mechanical allodynia (MA) in vivo[1].
CAS Number
[2396754-57-5]
UNSPSC
12352005
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/p38-α-mapk-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=CC=C2Br)=CC(NC3=CC=CC=C3)=CN1
Molecular Formula
C17H13BrN2O
Molecular Weight
341.20
References & Citations
[1]Visseq A, et al. Pyridin-2 (1H) one derivatives: A possible new class of therapeutics for mechanical allodynia. Eur J Med Chem. 2020 Feb 1;187:111917.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P38α

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