p38-α MAPK-IN-4

p38-α MAPK-IN-4

• CAS Number: 2396754-57-5
• UNSPSC Description: p38-α MAPK-IN-4 (Compound 69) is a selective p38α MAPK inhibitor with an IC50 of 1.5 µM. p38-α MAPK-IN-4 rapidly and strongly prevents the development of mechanical allodynia (MA) in vivo[1].
• Target Antigen: p38 MAPK
• Type: Reference compound
• Related Pathways: MAPK/ERK Pathway
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/p38-α-mapk-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(C2=CC=CC=C2Br)=CC(NC3=CC=CC=C3)=CN1
• Molecular Weight: 341.20
• References & Citations: [1]Visseq A, et al. Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia. Eur J Med Chem. 2020 Feb 1;187:111917.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported