P38-α MAPK-IN-10

• Description :

  P38-α MAPK-IN-10 (Compound 6) is the inhibitor for p38α with an IC50 of 4 nM[1].

• UNSPSC :

  12352005

• Target :

  P38 MAPK

• Related Pathways :

  MAPK/ERK Pathway

• Field of Research :

  Inflammation/Immunology

• Smiles :

  ClC1=CC=C(C2=C(C3=CC=NC(NC4CCCCC4)=N3)N(CCC)C(C5CCNCC5)=N2)C=C1Cl

• Molecular Formula :

  C27H34Cl2N6

• Molecular Weight :

  513.51

• References & Citations :

  [1]Basant N, et al., Modeling the binding affinity of p38α MAP kinase inhibitors by partial least squares regression. Chem Biol Drug Des. 2012 Sep;80 (3) :455-70.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  P38α

• CAS Number :

  [200801-77-0]