AAK1-IN-3

CAT: 0804-HY-144302Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144302Size:1 Each
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
AAK1-IN-3, a quinoline analogue, is a brain-penetrant adaptor protein 2-associated kinase 1 (AAK1) inhibitor with an IC50 of 11 nM. AAK1-IN-3 has the potential for neuropathic pain research[1].
CAS Number
[1802703-20-3]
UNSPSC
12352005
Target
AAK1
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aak1-in-3.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC([C@H](N)CC(C)C)=NC2=CC=C(C3=CC=NC=C3)C=C12
Molecular Formula
C20H20N4
Molecular Weight
316.40
References & Citations
[1]Richard A Hartz, et al. Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors. J Med Chem. 2022 Mar 10;65 (5) :4121-4155.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Popular Products