AAK1-IN-6
CAT:
804-HY-159879
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AAK1-IN-6
- UNSPSC Description: AAK1-IN-6 (Compound 23) is an inhibitor of AP-2-associated protein kinase 1 (AAK1, IC50 = 12 nM) with antiviral activity against the dengue virus (DNEV2, EC50 = 0.24 μM) and Venezuelan equine encephalitis virus (VEEV, EC50 = 0.30 μM). AAK1-IN-6 can be utilized in antiviral research[1].
- Target Antigen: AAK1; Dengue virus
- Type: Reference compound
- Related Pathways: Anti-infection;Neuronal Signaling
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/aak1-in-6.html
- Smiles: COC1=C(OC)C=C(C2=CN=C(NC=C3C4=CN=C(C5=CC=CC=C5)O4)C3=C2)C=C1
- Molecular Weight: 397.43
- References & Citations: [1]Ravi NP, et al. Synthesis of 3-heteroaryl-pyrrolo[2,3-b]pyridines as potent inhibitors of AP-2-associated protein kinase 1 (AAK1) with antiviral activity. Eur J Med Chem. 2024 Dec 15;280:116967.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported