MAT2A-IN-6

• Description :

  MAT2A-IN-6 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-6 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-6 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 18) [1].

• UNSPSC :

  12352005

• Target :

  Methionine Adenosyltransferase (MAT)

• Type :

  Reference compound

• Related Pathways :

  Epigenetics; Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mat2a-in-6.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C(NC)C2=C(N(C3=CC=CC=C3Cl)C1=O)N=C(C(F)(F)F)C=C2)OC

• Molecular Formula :

  C18H13ClF3N3O3

• Molecular Weight :

  411.76

• References & Citations :

  [1]Li Zhen, et al. Bicyclic compounds. Patent WO2021254529A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2756458-72-5]