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PIM1-IN-4

CAT: 0804-HY-143898Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143898Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PIM1-IN-4 (Compound 8) is a potent inhibitor of PIM1. PIM1-IN-4 reveals strong inhibition of five other enzymes, i.e., SGK-1, PKA, CaMK-1, GSK3β, and MSK1. PIM1-IN-4 has the potential for the research of cancer diseases[1].
CAS Number
2762767-48-4
UNSPSC
12352005
Target
Pim
Type
Reference compound
Related Pathways
JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pim1-in-4.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC=C(C2=C1)NC3=C2C4=C([N]5=C3N[N]6=C(C7=CC=C(C=[N]7[Cu]65(Cl)Cl)CN8CCOCC8)C)C=CC=C4
Molecular Formula
C27H25BrCl2CuN6O
Molecular Weight
663.88
References & Citations
[1]Wittmann C, et al. Highly Antiproliferative Latonduine and Indolo[2,3-c]quinoline Derivatives: Complex Formation with Copper (II) Markedly Changes the Kinase Inhibitory Profile. J Med Chem. 2022 Feb 10;65 (3) :2238-2261.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PIM1

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